Diabetes Type I–Risk to Family Members

Do you or a loved on have Diabetes Mellitus Type I and worry about the risk of other family members inheriting this disease. The genetic risk for Diabetes Type I was sited in a review course. For people with one sibling with diabetes Type I, the risk is about 10%. The risk is the same for twins that are not identical. For twins that are identical, the risk is about 50%. A woman with Diabetes has about a 4% chance of having a child with Diabetes Type I. If the father has type I Diabetes the risk to his offspring depends upon his age at onset. If he gets Diabetes before age 4 the risk to his offspring is 12%. Between ages 5-9 the risk deceases to 8.5%. Between ages of 10-14 the risk of his offspring developing diabetes type I is 6 %. Ages 15-19 the risk is 5%. A father with diabetes discovered between the ages of 20-30 has a risk of 3%. If either parent has signs of other autoimmune diseases that often coexist with diabetes type I such as Hashimoto’s disease (thyroid), Addison’s disease (insufficiency of the adrenal gland), Sprue, or other autoimmune diseases, the risk increases to about 50%. The reason for the different numbers in the Mother or the Father is not known. Do you or your children have Diabetes Type I. Please let us know so that we can see if our statistics are consistent with these numbers?

MEDICAL ADVICE DISCLAIMER: The information included on this site is for educational purposes only. It is not intended nor implied to be a substitute for professional medical advice. The reader should always consult his or her health care provider to determine the appropriateness of the information for their own situation, or if they have any questions regarding a medical condition or treatment plan. Reading the information on this website does not create a physician-patient relationship.

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4 Responses to Diabetes Type I–Risk to Family Members

  1. Dr. Sybil Kramer says:

    Thank you so much for visiting our website. A new onset of Type I diabetes can be overwhelming and having to cope with your own disease as well as helping your child through this must be so difficult. The risk for developing Diabetes Type I is much higher for people who have other associated autoimmune diseases. Maternal age of developing Diabetes Type I does not affect the chances of it going to the offspring as much as the age of the father upon diagnosis. Please feel free to join our face-book group, Diabetes Mastermind. Your children, if old enough are also invited to join and interact with other people with Diabetes type I and Type 2 as well. You may also want to check out our cooking videos with your children and choose meals that taste good and are diabetic friendly. Let us know how we may support you.

  2. Lisa Hart says:

    Thanks for the info. My daughter was diagnosed Type 1. Two days later, I was diagnosed with the same.

    I also have IgA deficiency, which I believe has been linked to T1 diabetes. Wondering if that would increase risk for my other two children developing T1.

  3. Dr. Sybil Kramer says:

    Thank you so much for visiting our website. The pathophysiology of Type I A Diabetes (autoimmune type) is believed to be an interaction between environmental triggers as well as genetic susceptibility. Associations between exposure has been attributed to ingestion of cows milk, virus (enteroviruses, congenital rubella) cereals in infancy, as well as maternal factors such as maternal age, preeclampsia. Mumps and chicken pox together, that certainly makes for a rough combination. I am glad your children and grandchildren are not affected. Congratulations on doing so well for 68 years.

  4. Richard Vaughn says:

    I have been T1 for 68 years, diagnosed when I was 6, and have good diabetes health. I have a sister, two sons and two grand children, none of whom have T1 diabetes. I do not think my T1 was genetic. I developed all the classic symptoms of T1 while recovering from mumps and chicken pox.

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